Friday, October 7, 2016

Acetazolamide Sustained-Release Capsules



Pronunciation: a-set-a-ZOLE-a-mide
Generic Name: Acetazolamide
Brand Name: Diamox Sequels


Acetazolamide Sustained-Release Capsules are used for:

Treating certain types of glaucoma in combination with other medicines. It is also used to treat or prevent symptoms of mountain sickness. It may also be used for other conditions as determined by your doctor.


Acetazolamide Sustained-Release Capsules are a carbonic anhydrase inhibitor. It reduces fluid pressure in the eyeball by decreasing fluid formation in the eyeball.


Do NOT use Acetazolamide Sustained-Release Capsules if:


  • you are allergic to any ingredient in Acetazolamide Sustained-Release Capsules

  • you have adrenal gland problems, low blood levels of potassium or sodium, kidney problems, liver problems (eg, cirrhosis), high blood levels of chloride, or other electrolyte problems

Contact your doctor or health care provider right away if any of these apply to you.



Before using Acetazolamide Sustained-Release Capsules:


Some medical conditions may interact with Acetazolamide Sustained-Release Capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have kidney stones, a lung disease, glaucoma (eg, chronic non-congestive angle-closure glaucoma), diabetes, or difficulty breathing

  • if you have had a severe allergic reaction (eg, a severe rash, hives, breathing difficulties, or dizziness) to any other sulfonamide medicine such as acetazolamide, celecoxib, certain diuretics (eg, hydrochlorothiazide), glyburide, probenecid, sulfamethoxazole, valdecoxib, or zonisamide

Some MEDICINES MAY INTERACT with Acetazolamide Sustained-Release Capsules. Tell your health care provider if you are taking any of the following medicines:


  • Salicylates (eg, aspirin) because they may increase the risk of Acetazolamide Sustained-Release Capsules's side effects

  • Other carbonic anhydrase inhibitors (eg, methazolamide), cyclosporine, quinidine, phenytoin, amphetamine, or sodium bicarbonate because the risk of their side effects may be increased by Acetazolamide Sustained-Release Capsules

  • Primidone, salicylates (eg, aspirin), lithium, or methenamine because their effectiveness may be decreased by Acetazolamide Sustained-Release Capsules

This may not be a complete list of all interactions that may occur. Ask your health care provider if Acetazolamide Sustained-Release Capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Acetazolamide Sustained-Release Capsules:


Use Acetazolamide Sustained-Release Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Acetazolamide Sustained-Release Capsules by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

  • Drinking extra fluids while you are taking Acetazolamide Sustained-Release Capsules are recommended. Check with your doctor for instructions.

  • Swallow Acetazolamide Sustained-Release Capsules whole. Do not break, crush, or chew before swallowing.

  • Acetazolamide Sustained-Release Capsules may increase the amount of urine or cause you to urinate more often when you first start taking it. To keep this from disturbing your sleep, try to take your dose before 6 pm.

  • If you miss a dose of Acetazolamide Sustained-Release Capsules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Acetazolamide Sustained-Release Capsules.



Important safety information:


  • Acetazolamide Sustained-Release Capsules may cause drowsiness or temporary vision changes. These effects may be worse if you take it with alcohol or certain medicines. Use Acetazolamide Sustained-Release Capsules with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • Acetazolamide Sustained-Release Capsules may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Acetazolamide Sustained-Release Capsules. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.

  • Tell your doctor or dentist that you take Acetazolamide Sustained-Release Capsules before you receive any medical or dental care, emergency care, or surgery.

  • Diabetes patients - Acetazolamide Sustained-Release Capsules may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.

  • Acetazolamide Sustained-Release Capsules may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Acetazolamide Sustained-Release Capsules.

  • Lab tests, including blood electrolyte levels, complete blood cell count, or platelet levels, may be performed while you use Acetazolamide Sustained-Release Capsules. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.

  • Use Acetazolamide Sustained-Release Capsules with caution in the ELDERLY; they may be more sensitive to its effects.

  • Acetazolamide Sustained-Release Capsules should be used with extreme caution in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Acetazolamide Sustained-Release Capsules while you are pregnant. Acetazolamide Sustained-Release Capsules are found in breast milk. Do not breast-feed while taking Acetazolamide Sustained-Release Capsules.


Possible side effects of Acetazolamide Sustained-Release Capsules:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Blurred vision; changes in taste; constipation; diarrhea; drowsiness; frequent urination; loss of appetite; nausea; vomiting.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blood in urine; changes in hearing; convulsions; dark, bloody stools; dark urine; fast breathing; fever; lack of energy; lower back pain; red, swollen, or blistered skin; ringing in the ears; sore throat; tingling of the arms or legs; unusual bleeding or bruising; vision changes; yellowing of the skin or eyes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Acetazolamide side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include abnormal skin sensations (eg, tingling, tickling, itching, burning); buzzing, ringing, or whistling in the ears; drowsiness; loss of appetite; loss of coordination; nausea; tremors; unsteady movements; vomiting.


Proper storage of Acetazolamide Sustained-Release Capsules:

Store Acetazolamide Sustained-Release Capsules at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Acetazolamide Sustained-Release Capsules out of the reach of children and away from pets.


General information:


  • If you have any questions about Acetazolamide Sustained-Release Capsules, please talk with your doctor, pharmacist, or other health care provider.

  • Acetazolamide Sustained-Release Capsules are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is summary only. It does not contain all information about Acetazolamide Sustained-Release Capsules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Acetazolamide resources


  • Acetazolamide Side Effects (in more detail)
  • Acetazolamide Use in Pregnancy & Breastfeeding
  • Drug Images
  • Acetazolamide Drug Interactions
  • Acetazolamide Support Group
  • 22 Reviews for Acetazolamide - Add your own review/rating


Compare Acetazolamide with other medications


  • Edema
  • Epilepsy
  • Glaucoma
  • Hydrocephalus
  • Mountain Sickness / Altitude Sickness
  • Pseudotumor Cerebri
  • Seizure Prevention

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